HPLC Quantitative Resolution of Acetaminophen, Dextromethorphan Hydrobromide, and Phenylephrine Hydrochloride in Powder Dosage Form by Chemometric Analysis Method
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منابع مشابه
RP-HPLC method development for the estimation of Levocetirizine and Phenylephrine hydrochloride in combined dosage form
A rapid, accurate RP Levocetirizine and phenylephrine separation was achieved on column Luna 5u C18 (20mm X 4mm) using mobile phase of methanol: Pot. Dihydrogen Phosphate Buffer (pH 6.0), (70:30) .The UV detection was performed at 251nm with flow rate of 1.0 mL Phenylephrine hydrochloride was found to be 8.42 min and 2.70 min with mean recovery 100.64 & 100.40% respectively. The proposed method...
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The present study reveals a simple isocratic RP-HPLC method for the simultaneous determination of dextromethorphan hydrobromide and levocetirizine dihydrochloride in a cough syrup. The separation of these compounds was achieved within 10 min on a Phenomenex (USA) C(18) analytical column, 250×4.0 mm i.d., using an isocratic mobile phase consisting of potassium dihydrogen phosphate buffer (pH 2.5...
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The aim of the present work was to develop and validate a simple, efficient and economical method for the analysis of Guaifenesin and Phenylephrine hydrochloride in bulk drug and pharmaceutical dosage forms by reverse phase high pressure liquid chromatography. A Zorbax reverse phase C18 column (150 x 3.0mm, 3.5μm) with mobile phase containing 5mM ammonium acetate: acetonitrile (80:20% v/v) was ...
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A RP-HPLC method was developed for the estimation of Atomoxetine Hydrochloride in tablet formulation, which is novel to the market. Chromatographic separation of the drug was achieved on a ENABLE C-18 G, 5μm, column (250 × 4.6 mm) using a mobile phase, Methanol: Ammonium phosphate buffer pH-3 (80:20 V/V) at a flow rate of 1ml/min. The drug eluted was monitored at 227 nm. The retention time was ...
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ژورنال
عنوان ژورنال: Indo Global Journal of Pharmaceutical Sciences
سال: 2020
ISSN: 2249-1023
DOI: 10.35652/igjps.2020.10110